Persistent tardive dyskinesia.

Persistent akathisia associated with early tardive dyskinesia.

Two psychiatric patients developed moderate or severe oro-facial dyskinesia, and limb dyskinesia, at a relatively young age and within a year of starting antipsychotic drug-treatment. This early appearance of tardive dyskinesia was preceded by akathisia that had developed at the beginning of drug therapy and persisted, despite the reduction of their drug doses to maintenance levels. The possibi...

A Case of Persistent Tardive Dyskinesia in Bipolar Mania

Bay CK 49 yaşında iki uçlu bozukluk tip 1 tanısı ile takipli, depresif dönemi olmayan Çin’li erkek hasta. Takibinde tam düzelme hiçbir zaman gelişmeyen hastanın hastalığına karşı içgörü azlığından dolayı 3 kere yatırılarak tedavi edildi. Hastanın beklenmeyen tardiv diskinezisi hipomanik dönemde hastalığının 15. yılından sonrasında ilk defa ortaya çıktı. Bu haraketler son manik döneminde arttı v...

Metoclopramide and tardive dyskinesia.

Metoclopramide (MCP) is a D-2 receptor blocker (Kebabian and Calne 1979), which has been available by prescription in the United States since 1979 for use as an antiemetic in a wide range of situations. One of the common indications for MCP is the &eatment of diabetic gastroparesis (Physicians' Desk Reference 1993). A few recent reports suggest that diabetes mellitus may be a risk factor for ta...

Sulpiride in tardive dyskinesia.

The abnormal involuntary movements in tardive dyskinesia can be reduced by the dopamine antagonist drugs, phenothiazines and butyrophenones, but most cause an increase in Parkinsonian signs. Sulpiride, a benzamide derivative, and selective antagonist of D2 receptors had a significantly beneficial effect on most of 15 patients (p less than 0.01). In 12 patients the improvement was marked. The re...

Clozapine-induced Tardive Dyskinesia